N-substituted aminomethyl-methoxy-heterocyclic compounds

Composes heterocycliques n-substitues aminomethyles et methoxyles


Abstract of the Disclosure 6.beta.-(Ra)(Rb)N-methylaryl-acetylamino-6.alpha.-methoxy-2,2-dimethyl-penam-3-carboxylic acid compounds and 7.beta.-(Ra)(Rb)N-methyl-aryl-acetylamino-7.alpha.-methoxy-3-cephem-4-carboxylic acid com-pounds, wherein one of the groups Ra and Rb represents optionally substituted lower alkyl and the other represents hydrogen or optionally substituted lower alkyl, or wherein Ra and Rb conjointly denote optionslly substituted lower alkylene, and wherein aryl represents thienyl .alpha.- furyl, and wherein the 3-position in 3-cephem compounds is unsubstituted or substituted by a modified hydroxyl group or an optionally substituted methyl group, exhibit antibiotic actions against Gram-negstive or Gram-positive microorganisms.




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